二叔丁基(2,4,6-三异丙酯- 3,6-二甲氧基联苯2基)膦
2-(Di-t-butylphosphino)-3,6-dimethoxy-2'-4'-6'-tri-i-propyl-1,1'-biphenyl,t-butylBrettPhos
CAS: 1160861-53-9
Molecular Formula: C31H49O2P
二叔丁基(2,4,6-三异丙酯- 3,6-二甲氧基联苯2基)膦 - Names and Identifiers
| Name | 2-(Di-t-butylphosphino)-3,6-dimethoxy-2'-4'-6'-tri-i-propyl-1,1'-biphenyl,t-butylBrettPhos |
| Synonyms | tBuBrettPhos t-butylBrettPhos tertButylBrettPhos tert-ButylBrettPhos -3,6-dimethoxybiphenyL 2-(Di-tert-butylphosphino)-2',4',6'-triisopropyl-3,6-diMethoxybiphenyl 2-Di-t-butylphosphino-2',4',6'-tri-i-propyl-3,6-diMethoxy-1,1'-biphenyl (t-BuBrettPhos) 2-(Di-t-butylphosphino)-3,6-dimethoxy-2'-4'-6'-tri-i-propyl-1,1'-biphenyl,t-butylBrettPhos |
| CAS | 1160861-53-9 |
| InChIKey | REWLCYPYZCHYSS-UHFFFAOYSA-N |
二叔丁基(2,4,6-三异丙酯- 3,6-二甲氧基联苯2基)膦 - Physico-chemical Properties
| Molecular Formula | C31H49O2P |
| Molar Mass | 484.69 |
| Melting Point | 166-170°C |
| Boling Point | 534.9±50.0 °C(Predicted) |
| Appearance | crystal |
| Color | white |
| Storage Condition | Room Temprature |
| Use | Use 2- (di-tert-butylphosphine)-3, 6-dimethoxy-2 ',4',6 '-triisopropyl-1, 1'-biphenyl belongs to a 2-dialkylphosphine -3, 6-dimethoxy-2 ',4',6 '-triisopropyl-1, 1'-biphenyl is an important class of organic phosphine ligands, complexing with transition metals can be used as catalysts for organic coupling reactions, and has a very wide range of applications in the synthesis of natural products, drugs, functional materials, liquid crystal molecules and bioactive compounds. |
二叔丁基(2,4,6-三异丙酯- 3,6-二甲氧基联苯2基)膦 - Risk and Safety
| WGK Germany | 3 |
二叔丁基(2,4,6-三异丙酯- 3,6-二甲氧基联苯2基)膦 - Nature
| melting point | 166-170°C |
| boiling point | 534.9±50.0 °C(Predicted) |
| morphology | crystal |
| color | white |
| InChIKey | REWLCYPYZCHYSS-UHFFFAOYSA-N |
Last Update：2024-04-10 22:29:15
二叔丁基(2,4,6-三异丙酯- 3,6-二甲氧基联苯2基)膦 - Introduction
2-(Di-t-butylphosphino)-3,6-dimethoxy-2 '-4'-6 '-tri-i-propyl-1,1'-biphenyl,t-butylBrettPhos, often abbreviated as DTBM-TPP.
Nature:
DTBM-TPP is an organic compound whose molecular formula is C38H54O2P2. It is a colorless crystalline solid. DTBM-TPP has high thermal stability and can exist stably at high temperatures. It is soluble in organic solvents but insoluble in water.
Use:
DTBM-TPP are mainly used as ligands or catalysts in chemical research to catalyze the synthesis of benzimidazolones and organic synthesis reactions. It can also be used as a light-emitting layer material for organic light-emitting diodes (OLEDs) with excellent fluorescent properties.
Preparation Method:
The method for preparing DTBM-TPP can be obtained by reacting phenylphosphoric acid with dimethoxybromobenzene in the presence of alkaline conditions, and then heating to obtain the target product. Specific synthetic routes may vary depending on experimental conditions and requirements.
Safety Information:
There is limited safety data on DTBM-TPP, so caution is required during handling and transportation. Avoid contact with skin and eyes and prevent inhalation or ingestion. Appropriate personal protective equipment, such as lab gloves and goggles, is recommended for use in a laboratory environment. If you have any health and safety issues, please follow the guidance of the laboratory safety operation and relevant regulations.
Nature:
DTBM-TPP is an organic compound whose molecular formula is C38H54O2P2. It is a colorless crystalline solid. DTBM-TPP has high thermal stability and can exist stably at high temperatures. It is soluble in organic solvents but insoluble in water.
Use:
DTBM-TPP are mainly used as ligands or catalysts in chemical research to catalyze the synthesis of benzimidazolones and organic synthesis reactions. It can also be used as a light-emitting layer material for organic light-emitting diodes (OLEDs) with excellent fluorescent properties.
Preparation Method:
The method for preparing DTBM-TPP can be obtained by reacting phenylphosphoric acid with dimethoxybromobenzene in the presence of alkaline conditions, and then heating to obtain the target product. Specific synthetic routes may vary depending on experimental conditions and requirements.
Safety Information:
There is limited safety data on DTBM-TPP, so caution is required during handling and transportation. Avoid contact with skin and eyes and prevent inhalation or ingestion. Appropriate personal protective equipment, such as lab gloves and goggles, is recommended for use in a laboratory environment. If you have any health and safety issues, please follow the guidance of the laboratory safety operation and relevant regulations.
Last Update：2024-04-10 22:29:15
二叔丁基(2,4,6-三异丙酯- 3,6-二甲氧基联苯2基)膦 - Uses and synthesis methods
| use | 2- (di-tert-butylphosphine)-3,6-dimethoxy -2 ',4',6 '-triisopropyl -1,1'-biphenyl belongs to a 2-dialkylphosphine -3,6-dimethoxy -2 ',4',6 '-triisopropyl -1,1'-biphenyl, which is an important organic phosphine ligand, it can be used as a catalyst for organic coupling reaction after complexing with transition metals, and has a very wide range of applications in the synthesis of natural products, drugs, functional materials, liquid crystal molecules and bioactive compounds. |
| preparation | under the protection of argon, the reaction solvent tetrahydrofuran 0.5L and magnesium metal (26g,1.1mol) are added to the drying reactor, then di-tert-butyl phosphine chloride (180g,1mol) is added at -10~10 ℃ for 2 hours, and then nickel catalyst Ni(acac)2(13g,0.05mol) and 2-bromo -3,6-dimethoxy -2 'are added',4 ',6'-triisopropyl -1,1 '-biphenyl (419g,1mol), then heated to 80 ℃ for 12 hours, then added 500mL of saturated ammonium chloride aqueous solution to quench the reaction, after liquid separation, organic phase concentration to remove solvent, methanol recrystallization to obtain 2-di-tert-butyl phosphine -3,6-dimethoxy -2',4, 90% yield. |
Last Update：2024-04-10 22:29:15
二叔丁基(2,4,6-三异丙酯- 3,6-二甲氧基联苯2基)膦 - Security information
| WGK Germany | 3 |
Last Update：2024-04-10 22:29:15
Supplier List
Spot supply
Product Name: tBuBrettPhos Visit Supplier Webpage Request for quotationCAS: 1160861-53-9
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: tBuBrettPhos Visit Supplier Webpage Request for quotationCAS: 1160861-53-9
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Product Name: 2-(Di-Tert-Butylphosphino)-2′,4′,6′- Triisopropyl-3,6-Dimethoxy-1,1′-Biphenyl Visit Supplier Webpage Request for quotation
CAS: 1160861-53-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 1160861-53-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Spot supply
Product Name: 2-Di-t-butylphosphino-3,6-dimethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl Request for quotationCAS: 1160861-53-9
Tel: 15001012717
Email: biz5@infsci.com
Mobile: 15001012717
QQ: 3007471201
Product List: View Catalog
Product Name: Di-tert-butyl(2',4',6'-triisopropyl-3,6-dimethoxybiphenyl-2-yl)phosphine Request for quotation
CAS: 1160861-53-9
Tel: 0086-13605431940
Email: xuli678323@126.com
Mobile: +86-13605431940
QQ: 56860987
WhatsApp: 13605431940
CAS: 1160861-53-9
Tel: 0086-13605431940
Email: xuli678323@126.com
Mobile: +86-13605431940
QQ: 56860987
WhatsApp: 13605431940
Spot supply
Product Name: tBuBrettPhos Visit Supplier Webpage Request for quotationCAS: 1160861-53-9
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: tBuBrettPhos Visit Supplier Webpage Request for quotationCAS: 1160861-53-9
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Product Name: 2-(Di-Tert-Butylphosphino)-2′,4′,6′- Triisopropyl-3,6-Dimethoxy-1,1′-Biphenyl Visit Supplier Webpage Request for quotation
CAS: 1160861-53-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 1160861-53-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Spot supply
Product Name: 2-Di-t-butylphosphino-3,6-dimethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl Request for quotationCAS: 1160861-53-9
Tel: 15001012717
Email: biz5@infsci.com
Mobile: 15001012717
QQ: 3007471201
Product List: View Catalog
Product Name: Di-tert-butyl(2',4',6'-triisopropyl-3,6-dimethoxybiphenyl-2-yl)phosphine Request for quotation
CAS: 1160861-53-9
Tel: 0086-13605431940
Email: xuli678323@126.com
Mobile: +86-13605431940
QQ: 56860987
WhatsApp: 13605431940
CAS: 1160861-53-9
Tel: 0086-13605431940
Email: xuli678323@126.com
Mobile: +86-13605431940
QQ: 56860987
WhatsApp: 13605431940
View History
二叔丁基(2,4,6-三异丙酯- 3,6-二甲氧基联苯2基)膦
TRISODIUM BIS[5-CHLORO-2-HYDROXY-3-[(2-HYDROXY-1-NAPHTHYL)AZO]BENZENESULPHONATO(3-)]COBALTATE(3-)
2-(5-乙基吡啶-2-基)乙胺双盐酸盐
BMS 814580
1-Cyclopentyl-3-mesityl-1H-imidazol-3-ium chloride
PERFLUORO(4-METHYLPENT-2-ENOIC ACID)
2-甲基-3-溴-5-硝基吡啶
ETHYL 4-[2-(4-METHYLPIPERAZINOMETHYL)PHENYL]-4-OXOBUTYRATE
喹啉-2-磺酰氟
ALPRAZOLAM USP C IV
TRISODIUM BIS[5-CHLORO-2-HYDROXY-3-[(2-HYDROXY-1-NAPHTHYL)AZO]BENZENESULPHONATO(3-)]COBALTATE(3-)
2-(5-乙基吡啶-2-基)乙胺双盐酸盐
BMS 814580
1-Cyclopentyl-3-mesityl-1H-imidazol-3-ium chloride
PERFLUORO(4-METHYLPENT-2-ENOIC ACID)
2-甲基-3-溴-5-硝基吡啶
ETHYL 4-[2-(4-METHYLPIPERAZINOMETHYL)PHENYL]-4-OXOBUTYRATE
喹啉-2-磺酰氟
ALPRAZOLAM USP C IV